Jobs in America

Research Scientist

5 Year

Full time work offers a different kind of work experience - is that something you're looking for? You have the possibility to negotiate your salary with the employer based on the company's approach to employee teamwork and collaboration. January 2, 2024 marked the start of the job listing for the Research Scientist position, which will expire on April 1, 2024. Work experience in the same field for a minimum of 60 months is a non-negotiable requirement for this job. Although the vacancy is based in Boston, it may be possible for interested candidates from anywhere to apply if they meet the necessary qualifications.

Research Scientist

- (3271979)


The Medical Practice Evaluation Center (MPEC) has an opportunity for an enthusiastic and energetic individual to join our research team investigating the clinical and economic value of alternative strategies of HIV and tuberculosis diagnosis, treatment, and prevention, as well as modeling of other diseases and care. The position is with an internationally-recognized, multidisciplinary team from Massachusetts General Hospital, Harvard Medical School, Harvard T.H. Chan School of Public Health, Yale School of Public Health, and multiple international institutions including the University of Cape Town, South Africa. The research team includes decision scientists, physicians, epidemiologists, biostatisticians, and health economists. Together, the group studies the clinical impact and cost-effectiveness of various prevention and treatment options for HIV/AIDS, tuberculosis, tobacco use, and other health-related conditions, in collaboration with researchers in the US, as well as in a range of international settings, including Botswana, Brazil, Côte d’Ivoire, France, India, Mozambique, South Africa, Thailand, and Zimbabwe.

The candidate should be highly motivated with extensive experience in quantitative methods, independent mathematical model development, parameterization, and debugging. The position offers a stimulating and multidisciplinary environment and the opportunity to contribute to the development of the NIH-funded Cost-effectiveness of Preventing AIDS Complications (CEPAC) microsimulation model, and potentially other disease models. The primary responsibilities of this individual will be to assist with model refinement and extension including infection transmission dynamics, to conduct CEPAC model-based cost-effectiveness analyses including value-of-information analyses, to lead in abstract and manuscript preparation, and to assist with grant submissions. There are multiple possibilities for interaction with other researchers in Boston, as well as collaboration with many national and international research groups and institutions.

Interested candidates should apply via

**When applying, please include a cover letter along with your resume.**

For more information regarding our group, please visit


Responsibilities include, but are not limited to, the following activities:

  • Lead US and international projects to complete the aims of numerous NIH grants, including development and specification of mathematical simulation models
  • Conduct multiple clinical and cost-effectiveness analyses on different aspects of HIV and tuberculosis disease management using a computer simulation model of HIV and tuberculosis disease (the CEPAC-US, CEPAC-International, CEPAC-Adolescent, and CEPAC-Pediatric models), assuring consistency with guidelines for best practices
  • Develop and apply novel simulation modeling methods, including value-of-information analysis, to inform clinical trial design in HIV and tuberculosis
  • Design methods of HIV and tuberculosis transmission modeling
  • Perform literature reviews and synthesize relevant data for these projects with biostatistics staff; work with these staff to convert published data into appropriate input parameters
  • Assist with the parameterization and documentation of the model, and train other users on updates
  • Develop analysis plans and protocols for studies consistent with federal guidelines
  • Troubleshoot model inconsistencies (bugs) alongside the Programming team and other research staff (Research Assistants and Project Managers)
  • Provide guidance to Research Assistants, particularly regarding methodological issues
  • Provide input into major studies undertaken by the research team
  • Lead abstract and manuscript preparation, as well as presentation of study results for several projects ata time
  • Prepare grant applications and related documents
  • Attend national and international scientific meetings
  • Present research at seminars, working group meetings, and lectures
  • Take a major role in technology transfer and training meetings with US and international investigators
  • Coordinate design of specific studies, collaborating with US and international collaborators across multiple sites
  • Assist in the training of new employees in the use of the CEPAC model
  • Other duties as assigned


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Duties will be carried out in a typical in-person office environment. Occasional evening or weekend work may be required.


Supervisory responsibilities include overseeing the analytic work conducted by fellows, graduate students, post-docs, and other researchers on assigned projects within the MPEC as needed.

The above is intended to describe the general contents and requirements of work being performed by people assigned to this classification. It is not intended to be construed as an exhaustive statement of all duties, responsibilities, or skills of personnel so classified.


Job qualifications include the following:

  • PhD or ScD in Operations Research, Decision Science, Systems Engineering, Industrial Engineering, Biostatistics, Epidemiology, or related area
  • Minimum of 5 years of research experience (inclusive of graduate studies)


  • Capacity to manipulate large amounts of data
  • Ability to work with mathematical models and methods, including Markov and Monte Carlo simulation models, compartmental and agent-based epidemiological models, and deterministic and probabilistic sensitivity analysis, and ability to solve technical problems in these areas
  • Experience with transmission or network modeling
  • Outstanding writing, presentation, and organizational skills for manuscript and abstract preparations
  • Facility with data analytic, statistical, and programming software
  • Proficiency with standard office software (Microsoft Word, Excel, and PowerPoint) and the ability to learn new computer applications
  • Ability to work independently as well as part of a team
  • Intellectual independence and initiative
  • Ability to supervise Research Assistants and other team members in collaborative projects
  • Experience in public health, health economics, and health policy, preferably in HIV or tuberculosis
  • Ability to work within NIH and other federal and foundation regulations and guidelines

This description has been designed to indicate the general nature and level of work performed by an employee within this position. The actual duties, responsibilities, and qualifications may vary based on need.

EEO Statement

Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives, and ideas, we choose to lead.

Primary Location MA-Boston-MGH Main Campus Work Locations MGH Main Campus 55 Fruit Street Boston 02114 Job Technician/Technologist/Scientist Organization Massachusetts General Hospital(MGH) Schedule Full-time Standard Hours 40 Shift Day Job Employee Status Regular Recruiting Department MGH Medicine Job Posting Jan 1, 2024

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